Various regimens are available for induction therapy for MCL. Guidelines from the NCCN recommend that patients with stage II bulky or stage III-IV MCL who show a partial response to induction therapy be considered for second-line therapy to achieve a complete response.
ISRT with or without chemoimmunotherapy may be considered for patients with stage I or stage II nonbulky MCL.
For patients with stage II bulky or stage III-IV MCL who are not candidates for stem cell transplant, less aggressive therapy is recommended.
Treatment with a BTK inhibitor is not a recommended first-line option.
Learn more about additional MCL management considerations and recommendations.
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Any views expressed above are the author's own and do not necessarily reflect the views of WebMD or Medscape.
Cite this: Elwyn C. Cabebe, Ann S. LaCasce. Fast Five Quiz: Management of Mantle Cell Lymphoma - Medscape - Jan 26, 2023.
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