Fast Five Quiz: Workup for Chronic Lymphocytic Leukemia

Mohammad Muhsin Chisti, MD; Karl J. D'Silva, MD


May 18, 2023

Chronic lymphocytic leukemia (CLL) is characterized by the clonal proliferation and accumulation of mature, typically CD5-positive B cells within the blood, bone marrow, lymph nodes, and spleen. The diagnosis of CLL is usually established by blood counts with differential, a blood smear, and immunophenotyping.

The incidence of CLL increases with age, making it likely that the prevalence and mortality of CLL will increase in coming years due to demographic shifts. In addition, the percentage of younger patients with early-stage CLL and minimal symptoms appears to be increasing as routine blood testing becomes more common.

How familiar are you with the workup for CLL? Test your knowledge with this quick quiz.


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