Fast Five Quiz: Workup for Chronic Lymphocytic Leukemia

Mohammad Muhsin Chisti, MD


November 30, 2021

The presence of < 5 × 109/L B lymphocytes in the absence of either lymphadenopathy or organomegaly (as discovered by physical examination or imaging studies), or of disease-related cytopenias or symptoms, is considered diagnostic for MBL. Gumprecht nuclear shadows, or smudge cells, found as cellular debris are further morphologic features frequently associated with CLL.

Learn more about the workup for CLL.


Comments on Medscape are moderated and should be professional in tone and on topic. You must declare any conflicts of interest related to your comments and responses. Please see our Commenting Guide for further information. We reserve the right to remove posts at our sole discretion.