Fast Five Quiz: Presentation and Diagnosis of Alpha-1 Antitrypsin Deficiency

Dora E. Izaguirre Anariba, MD


November 23, 2021

Alpha-1 antitrypsin deficiency (AATD) is a relatively common but frequently underrecognized disorder. It is considered the most common hereditary disorder in adults. It is associated with various clinical manifestations, mainly characterized by reduced serum levels of alpha-1 antitrypsin as well as an increased risk of developing lung and liver diseases at an early age. Although it is common, AATD is underdiagnosed. An estimated 3.4 million individuals worldwide are affected by AATD, and it is believed that approximately 117 million individuals are carriers of the disease. Delayed diagnosis may lead to adverse clinical outcomes.

How familiar are you with the presentation and diagnosis of AATD? Test your knowledge with this quick quiz.


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