Fast Five Quiz: Presentation and Diagnosis of Alpha-1 Antitrypsin Deficiency

Dora E. Izaguirre Anariba, MD

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November 23, 2021

The initial symptoms of AATD are intermittent and usually include cough, sputum production, and wheezing. Patients with predominate wheezing are often misdiagnosed with asthma, whereas those with recurrent episodes of cough may be treated with multiple courses of antibiotics and are evaluated for sinusitis, postnasal drip, or gastroesophageal reflux.

Panniculitis is a recognized but rare consequence of AATD and presents as migratory, painful red nodules on the skin.

Learn more about the manifestations of AATD.

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