No drugs are effective in treating ASPD itself; however, medications to treat various facets and co-occurring conditions are highly recommended. Second-generation antipsychotics (eg, risperidone, quetiapine) are used as first-line therapy to address aggressive behavior. Anticonvulsants (eg, oxcarbazepine, carbamazepine) can be used to aid with impulsivity. No psychological or psychotherapeutic strategies have shown clear efficacy with these patients, including in group settings, as they may be disruptive to other patients. Drugs for ADHD (eg, atomoxetine, bupropion) are often used to treat ADHD in ASPD as they are nonaddictive and people with ASPD are at elevated risk. For that reason, Adderall or any other addictive medication would not be recommended for use in this population.
Learn more about medication use in personality disorders.
This Fast Five Quiz was excerpted and adapted from the Medscape article Personality Disorders.