Fast Five Quiz: Antisocial Personality Disorder (Sociopathy)

Stephen Soreff, MD


November 11, 2021

The most successful treatment of antisocial personality disorder is early intervention in children with conduct disorder. Although various psychopharmacology and psychotherapy strategies have been attempted, none have shown clear efficacy, and many are associated with potential harms.

Hospitalization provides little to no benefit to patients with antisocial personality disorder. Furthermore, the presence of patients with this condition in a psychiatric hospital may prove disruptive and detrimental to the care of others. Typically, hospitalization is reserved for complications or co-occurring conditions. However, many patients with an antisocial personality have been incarcerated.

No drugs are effective in treating antisocial personality disorder itself, but medications to treat various facets and co-occurring conditions are highly recommended. Second-generation antipsychotics (risperidone, quetiapine) are used as first-line therapy to address aggressive behavior. Selective serotonin reuptake inhibitors (sertraline, fluoxetine) and mood stabilizers are second-line, with lithium and carbamazepine third-line. Anticonvulsants may help with impulsivity.

Read more on the treatment of personality disorders.

This Fast Five Quiz was excerpted and adapted from the Medscape Drugs & Diseases article Personality Disorders.

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