Some patients with relapsed multiple myeloma will not present with associated symptoms, but for others, progressive disease may manifest with prominent symptoms or significant organ dysfunction, such as cytopenias (especially anemia), bone or soft-tissue plasmacytomas, hypercalcemia, or renal failure. Relapsed multiple myeloma may also manifest as biochemical progression based on an increase in the paraprotein concentration.
Learn more about presentation of multiple myeloma.
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Cite this: Maria-Victoria Mateos. Fast Five Quiz: Relapsed/Refractory Multiple Myeloma - Medscape - Jan 11, 2022.