Fast Five Quiz: Type 2 Diabetes in the Intensive Care Setting

Anne L. Peters, MD


January 25, 2022

In the NICE-SUGAR trial, critically ill patients with diabetes were randomized to intensive glycemic control (80-110 mg/dL) or moderate glycemic control (140-180 mg/dL). The study found no significant treatment advantage among patients in the intensive control arm vs the moderate control cohort. In fact, slightly but significantly higher mortality rates (27.5% vs 25%) were associated with more intensive glucose control. The intensively treated cohort also had 10 to 15-fold greater rates of hypoglycemia, which may have contributed to the increase in mortality.

Learn more about the management of type 2 diabetes in different settings.


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