CRISPR was inspired by nucleic acid–based mechanisms that bacteria deploy to recognize and remove invading viral genomes. More than a decade ago, researchers discovered how bacteria fought off viruses. These and other microorganisms defend against infections by recording the DNA sequences of previous invaders so that when they return, the immune systems are precisely primed to overcome them.
To craft that genetic snapshot, the bacteria steal fragments of the intruder's genetic code.
Learn more about the rationale for CRISPR technology.
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Cite this: Kiran Musunuru. Fast Five Quiz: Genomic Medicine — CRISPR Gene Editing - Medscape - Dec 23, 2021.