Breast-conserving surgery is discouraged in patients carrying germline pathogenic variants in genes associated with high breast cancer risk, due to the risk of developing new breast tumors or recurrences. Genes that are known to confer high susceptibility to breast cancer include pathogenic variants in BRCA1 and BRCA2. Patients with inherited high-risk genetic traits may be considered for prophylactic bilateral mastectomy to reduce their risk.
All patients should undergo regular follow-up after a diagnosis of invasive breast cancer.
Learn more about reducing recurrence of breast cancer in patients who are high-risk.
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Cite this: Elwyn C. Cabebe, Stefania Morganti. Fast Five Quiz: The Recurrence Risks for Breast Cancer - Medscape - Feb 06, 2023.