Fast Five Quiz: Helicobacter pylori–Associated Gastritis

Steven F. Moss, MD


January 25, 2022

Figure 1. Endoscope view of gastritis.

Patients with H pylori–associated gastritis may have antral-predominant inflammation or corpus-predominant gastritis. Corpus-predominant gastritis leads to hypochlorhydria (low levels of stomach acid) and predisposes individuals to gastric ulceration and adenocarcinoma. Antral-predominant inflammation leads to increased acid production from the uninflamed corpus and predisposes individuals to duodenal ulceration.

Gastritis caused by H pylori decreases somatostatin levels, which negatively affects gastrin secretion.

H pylori is the leading cause of chronic gastritis and the principal etiologic agent for gastric cancer and peptic ulcer disease.

Learn more about H pylori–associated gastritis.


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