Fast Five Quiz: Overview of Pediatric Respiratory Syncytial Virus

Asif Noor, MD


March 03, 2022

Young chronological age and prematurity are risk factors for severe disease and hospitalization. Even though the greatest risk for severe disease is in premature infants who are born at 29 weeks' gestation or earlier, recent data continue to demonstrate that there is an increased risk in infants who are born at up to 35 weeks' gestation.

A multicenter SENTINEL 1 study by Anderson and colleagues reported that preterm infants who are 29-35 weeks of gestational age are at high risk for severe RSV disease. In the study, of 702 infants who were hospitalized with community-acquired RSV, 42% were admitted to the intensive care unit and 20% required invasive mechanical ventilation. Moreover, 68% of the infants who were 29-32 weeks of gestational age and under 3 months of age required intensive care unit admission and 44% required invasive mechanical ventilation.

Childcare attendance, having older siblings in school, and lower socioeconomic status are some of the factors associated with increased risk for community-acquired RSV.

Learn more about the etiology of RSV.


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