Involvement of ≥ 10% BSA is one of the key features of moderate to severe AD. However, there are other determinants of severity that may take precedence regardless of the extent of BSA involved. If the lesions are in areas that are highly visible or important for function (soles, palms, neck, and face), the disease may still be considered moderate to severe even if involved BSA is < 10%; the same applies to severe itch and significantly reduced quality of life (interference with sleep or daily activities). On the basis of any of these criteria, the girl described above has moderate to severe AD.
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Cite this: Diamant Thaçi. Skill Checkup: An 11-Year-Old Girl With Severe Nighttime Itchiness - Medscape - Apr 14, 2022.