Vaccinations in Adults Clinical Practice Guidelines (ACIP, 2022)

Advisory Committee on Immunization Practices

These are some of the highlights of the guidelines without analysis or commentary. For more information, go directly to the guidelines by clicking the link in the reference.

March 01, 2022

The 2022 recommended adult immunization schedule for the United States was published in February 2022 by the Advisory Committee on Immunization Practices (ACIP) of the Centers for Disease Control and Prevention (CDC) in  Annals of Internal Medicine[1]  and  Morbidity and Mortality Weekly Report.[2]

Hepatitis B: Universal vaccination of all adults aged 19 through 59 years, and vaccination of adults aged 60 years and older at risk for hepatitis B virus infection, are recommended. Additionally, ACIP recommends vaccination of adults aged 60 years and older who request HBV vaccination, without the need to identify a specific risk factor.

Influenza: For the 2021-2022 influenza season, ACIP recommends routine annual influenza vaccination for all individuals aged 6 months and older who have no contraindications. The committee does not recommend one influenza vaccine product over another in individuals for whom more than one licensed and recommended product is appropriate. For example, a previous severe allergic reaction to influenza vaccine is not a contraindication against future influenza vaccination; these individuals may be able to receive a different type of influenza vaccine.

Pneumococcal Vaccine: Routine vaccination is recommended for all adults aged 65 years or older. Those aged 65 and older who have not previously been given a pneumococcal conjugate vaccine (PCV) or who have an unknown vaccination history should get one dose of PCV15 or one dose of PCV20. If PCV15 is given, this should be followed by a dose of PPSV23.

Individuals aged 19 through 64 years with specific underlying medical conditions or other risk factors who have not previously been given a pneumococcal conjugate vaccine or who have an unknown vaccination history should get one dose of PCV15 or one dose of PCV20. If PCV15 is given, this should be followed by a dose of PPSV23.

Vaccination During the Coronavirus Disease 2019 (COVID-19) Pandemic: ACIP recommends vaccination in the patient’s medical home and encourages providers to give all due and overdue vaccines in accordance with the routine immunization schedule during the same visit. Providers should use strategies to get patients caught up on any overdue vaccines. 

For more information, please go to Measles, Mumps, Pediatric Rubella, Haemophilus Influenzae Infections, Hepatitis B, Human Papillomavirus, Influenza, Meningococcemia, Pneumococcal Infections (Streptococcus pneumoniae), Varicella Zoster Virus, Zoster Vaccine Recombinant, Coronavirus 2019 (COVID-19), and COVID-19 Vaccines.

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