Fast Five Quiz: Advanced and Metastatic Gastric Cancer

Elwyn C. Cabebe, MD


April 06, 2022

Because of lower toxicity, two-drug cytotoxic regimens (eg, fluoropyrimidine and oxaliplatin) are preferred for patients with advanced disease.

Perioperative chemotherapy (eg, FLOT), or postoperative chemotherapy plus chemoradiation (fluorouracil [5-FU] or capecitabine + oxaliplatin plus infusional fluoropyrimidine), is preferred for localized gastric cancer.

Two-drug regimens are preferred because of lower toxicity. Three-drug regimens should be reserved for patients who are medically fit and have access to frequent follow-up. Oxaliplatin is generally preferred over cisplatin owing to lower toxicity.

Learn more about gastric cancer treatment.


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