Identifying histologic type is needed for NSCLC, as treatment for stage IV disease is based on the presence of squamous or nonsquamous histology. In addition, identifying PD-L1 status is needed to help identify those who may be responsive to first-line immunotherapy.
Performing a complete blood cell count with differential as well as serum chemistry is part of an initial workup. Results of a complete blood cell count can aid in determining whether an infiltrate is potentially infectious in patients with metastatic disease.
Bone scintigraphy should be performed on patients who reported bone pain, as the skeletal system is a common site for metastases.
Learn more about the workup for metastatic NSCLC.
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Cite this: Winston W. Tan. Fast Five Quiz: Metastatic Non–Small Cell Lung Cancer - Medscape - Mar 29, 2022.