Rapid Review Quiz: Pneumococcal Infections

Michael Stuart Bronze, MD


March 11, 2022

In a recent study, severely ill patients with CAP and high inflammatory responses received 28-day mortality benefits from corticosteroid therapy. Mortality was significantly lower among patients with septic shock and/or who required invasive mechanical ventilation and who received corticosteroids. Corticosteroid use reduced the 28-day mortality risk in patients who met major severity criteria (hazard ratio [HR], 0.53; 95% CI, 0.29-0.98; P = .043). No benefits were observed with corticosteroid use (HR, 0.88; 95% CI, 0.32-2.36) in patients who did not meet major severity criteria.

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