Fast Five Quiz: Progressive Fibrosing Interstitial Lung Disease

Zab Mosenifar, MD, FACP, FCCP


April 12, 2022

A predominant symptom of all CTDs is insidious onset of dyspnea, especially on exertion, chronic cough, hypoxia, and, in the later stages of ILD, hypoxemia. Occasional chest pain is also reported. Patients are often asymptomatic early in the disease course.

Rash (along with fever and joint pain) is part of the classic presentation of systemic lupus erythematosus, a chronic inflammatory disease that can cause ILD but also involves other systems, including the skin, joints, kidneys, blood cells, and nervous system.

Clinically, patients with RA-ILD develop dyspnea with occasional dry cough; another primary symptom is joint pain.

Nail fold telangiectasia, or nail pitting, is a common characteristic of scleroderma, a connective tissue disease that also involves subcutaneous tissue, muscles, and internal organs.

Learn more about the clinical presentation of CTD-ILDs.


Comments on Medscape are moderated and should be professional in tone and on topic. You must declare any conflicts of interest related to your comments and responses. Please see our Commenting Guide for further information. We reserve the right to remove posts at our sole discretion.