Rapid Review Quiz: Long COVID

Michael Stuart Bronze, MD


March 22, 2022

Of the 15 studies included, seven examined vaccination before infection and its impact on long COVID incidence and/or symptoms, seven examined vaccination after infection, and one study examined both.

Patients who were vaccinated soon after diagnosis were much less likely to report symptoms of long COVID than were patients who remained unvaccinated. Vaccinated people were less likely to develop long COVID symptoms after infection in the short term (4 weeks after infection), medium term (12-20 weeks after infection) and long term (6 months after infection). Fully vaccinated people were less likely than unvaccinated people to have each of the following symptoms in the medium or long term: anosmia, dizziness, fatigue, hair loss, headache, interstitial lung disease, myalgia, persistent muscle pain, shortness of breath, weakness in arms and legs, and other pain. More patients with long COVID reported unchanged symptoms after vaccination than either people reporting better or worse symptoms.

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