Fast Five Quiz: Type 2 Diabetes and Obesity and Weight Management

Anne L. Peters, MD; Romesh Khardori, MD, PhD


February 22, 2023

Weight loss medications should be considered as an adjunct to lifestyle modifications in patients with type 2 diabetes who fail to respond to lifestyle interventions after 6 months and who have a BMI ≥ 27. Weight loss medication may help patients adhere to dietary recommendation, enabling initial weight loss and preventing weight regain. Pharmacotherapy should be continued in patients who achieve ≥ 5% weight loss after 3-4 months with one weight loss medication. In addition, pharmacotherapy may benefit patients prior to and following weight loss surgery to achieve greater total weight loss.

Phentermine is a sympathomimetic anorexigenic agent approved for short-term management of obesity. It is contraindicated in individuals with uncontrolled hypertension, CVD, hyperthyroidism, glaucoma, or recent use of monoamine oxidase inhibitors.

Learn more about the pharmacologic therapy for type 2 diabetes.


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