Bile acid sequestrants bind with bile acids in the intestines, preventing the reabsorption of bile acids. They reduce LDL levels by approximately 15%-30%. Studies have demonstrated that cholestyramine may decrease cardiovascular mortality and morbidity by 19% compared with patients on placebo. In addition, bile acid sequestrants can reduce blood sugar levels, benefiting patients with type 2 diabetes.
Fibrates and nicotinic acid may raise high-density lipoprotein cholesterol levels but have not been shown to improve cardiovascular outcomes in patients on statins. Similarly, the STRENGTH trial found no benefit in fish oil supplementation in the incidence of major adverse cardiovascular events in high-risk patients.
Learn more about type 2 diabetes.
Medscape © 2022 WebMD, LLC
Any views expressed above are the author's own and do not necessarily reflect the views of WebMD or Medscape.
Cite this: Anne L. Peters. Fast Five Quiz: Type 2 Diabetes and Dyslipidemia - Medscape - May 16, 2022.