Fast Five Quiz: Type 2 Diabetes and Dyslipidemia

Anne L. Peters, MD


May 16, 2022

Patients with type 2 diabetes and established CVD are at very high risk for major adverse cardiovascular events. If an LDL of < 70 mg/dL is unable to be achieved with the maximally tolerated dose of statins and cholesterol absorption inhibitor, such as ezetimibe, the American College of Cardiology and European Society of Cardiology recommend the addition of a PCSK9 inhibitor. These recommendations were made after the FOURIER clinical trial demonstrated that PCSK9 inhibitors, such as evolocumab and alirocumab, are associated with a significantly lower risk for cardiovascular events: stroke, myocardial infarction, and coronary revascularization.

Icosapent ethyl may be an option to lower triglycerides in patients being treated with statin therapy. In randomized trials, icosapent ethyl was demonstrated to improve the risk for subsequent ischemic events in patients with a history of prior percutaneous coronary intervention.

Learn more about type 2 diabetes.


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