For the management of type 2 diabetes in pregnancy, insulin is the preferred agent; injections and insulin pump therapy are both effective. Insulin management in pregnancy is complex and requires intense glucose monitoring. Recommended glucose targets are fasting glucose target 70-95 mg/dL (in preexisting diabetes), 110-140 mg/dL 1-hour postprandial, and 100-2120 mg/dL 2-hour postprandial, and the A1C should be < 6.0%. In addition, unlike metformin and sulfonylureas, insulin has not been shown to cross the placenta.
Although aspirin does not affect blood glucose levels, it may reduce the risk for preeclampsia in patients with type 2 diabetes. Studies have demonstrated a lower incidence of preeclampsia in high-risk patients treated with low-dose aspirin.
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Cite this: Anne L. Peters. Fast Five Quiz: Type 2 Diabetes and Pregnancy - Medscape - May 11, 2022.