Rapid Review Quiz: Cancer Overdiagnosis

Elwyn C. Cabebe, MD


April 08, 2022

Gao and colleagues found that when LDCT lung cancer screening was promoted to a population with a smoking prevalence of less than 5%, the screening was associated with significant overdiagnosis and high 5-year survival rates. Specifically, the incidence of stage 0-I lung cancer increased from 2.3 per 100,000 population to 14.4 per 100,000 population, even as the incidence of stage II-IV lung cancer remained virtually unchanged. The authors concluded that because a decline in late-stage cancer did not accompany the increase in detection of early stage cancer, nearly all the increased detection represents overdiagnosis.

Learn more about non–small cell lung cancer.


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