Rapid Review: Sepsis

Richard H. Sinert, DO


April 08, 2022

A recent retrospective analysis found that most patients with sepsis acquired it before ICU admission; however, patients who acquired sepsis in ICU the had worse outcomes. Sepsis was identified in around 60% of emergency ICU admissions, based on the Sepsis-3 operational criteria for sepsis.

The cohort used a broad range of antibiotics, and researchers found high reliance on broad- and extended-spectrum antibiotics. Compared with emergency patients admitted without a sepsis diagnosis, patients admitted with sepsis without shock had better survival rates; however, patients with septic shock had significantly worse outcomes. Overall mortality rates for ICU patients with sepsis were consistent with previous research.

Learn more about hospital-acquired infections.


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