Fast Five Quiz: Peripheral Arterial Occlusive Disease Signs and Symptoms

Arnold S. Baas, MD


May 17, 2022

Peripheral arterial occlusive disease (PAOD) is a manifestation of systemic atherosclerosis and characterized by decreased lower extremity arterial perfusion. The prevalence of PAOD increases significantly with age and affects a large fraction of the elderly population. In most cases, atherosclerotic plaques narrow the arterial flow lumen and restrict blood flow to the distal extremity. Patients experience a variable disease presentation and course; some remain asymptomatic, while others may progress to arterial ulceration, resting limb ischemia, and limb loss. One of the most common manifestations of PAOD is claudication caused by atherosclerosis.

It is well established that when patients with PAOD are treated with risk factor modifying and antithrombotic therapies, the risk for major adverse cardiovascular events and major adverse limb events decreases. However, patients with PAOD are undertreated compared with patients with coronary artery disease (CAD). Therefore, recognizing the signs and symptoms of the condition is critical.

Can you recognize the signs and symptoms of PAOD? Test your knowledge with this quick quiz.


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