Recent research has shown that posttraumatic amnesia and chronic vascular lesions caused by traumatic brain injury (TBI) increase risk for subsequent Alzheimer's disease. Evidence also suggests that TBI lowers the age of dementia onset; early-onset Alzheimer's disease has a higher prevalence of TBI.
Other notable differences between early-onset Alzheimer's disease and common late-onset disorder include:
Longer delay in diagnosis
Decreased cardiovascular fitness
Less incidence of diabetes, obesity, circulatory disorders
Increased psychosocial problems
More aggressive course
Greater white matter changes, especially in posterior association areas and frontoparietal networks
Learn more about the presentation of Alzheimer's disease.
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Any views expressed above are the author's own and do not necessarily reflect the views of WebMD or Medscape.
Cite this: Helmi L. Lutsep. Fast Five Quiz: Alzheimer's Disease - Medscape - May 06, 2022.
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