Fast Five Quiz: Kidney Transplant Rejection Risk and Monitoring

Phuong-Thu Pham, MD, FASN


May 19, 2022

HLA typing plays a pivotal role in matching donor to recipient. HLAs are groups of cell surface glycoproteins that are encoded by the major histocompatibility complex genes. They are used by cells to distinguish self from nonself. Exposure to nonself HLA can cause an immune response in the recipient. The development of anti-HLA antibodies directed against the donor (also known as donor-specific antibodies) increases the likelihood of kidney rejection.

Other pretransplant studies include chest radiography, pulmonary studies, noninvasive vascular studies, serologic tests, and abdominal and renal ultrasonography. Bladder capacity and functional studies may be needed, if indicated.

Learn more about pretransplant studies.


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