Fast Five Quiz: Kidney Transplant Rejection Risk and Monitoring

Phuong-Thu Pham, MD, FASN


May 19, 2022

Living donation allows optimal preparation of both the donor and recipient and minimizes the time an organ needs to be preserved (also known as cold ischemia time).

According to the UNet database supported by UNOS, the incidence of living donor kidney donation increased beginning in the mid-1990s and has ranged from 5500 to > 6800 between 2000 and 2019.

Switching from flank incision to laparoscopic technique resulted in major improvements for donor nephrectomy, including reducing hospital stay length by several days and limiting subsequent recovery times to several weeks.

A waiting list is used for allocation of deceased donor transplants. Patients with high calculated PRA score are given prioritization points to increase their probability of transplantation (Gebel and colleagues). PRA (expressed as percentage) estimates the percentage of organ donors who would be crossmatch positive with a transplant candidate in a given donor pool tested. High PRAs have been shown to be associated with increased risk for rejection.

Learn more about kidney transplantation technique.


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