Rapid Rx Quiz: Diabetes Drugs

Mary L. Windle, PharmD


May 13, 2022

Diarrhea is common with immediate-release formulations of metformin and is a major reason for discontinuing the drug. Aside from diarrhea, common adverse effects of metformin include:

  • Diarrhea, immediate-release product (53%)

  • Nausea/vomiting, immediate-release product (25%)

  • Diarrhea, extended-release product (10%)

  • Nausea/vomiting, extended-release product (7%)

  • Low serum vitamin B12 (7%)

  • Abdominal pain (1%-5%)

  • Constipation (1%-5%)

  • Abdomen distention (1%-5%)

  • Dyspepsia/heartburn (1%-5%)

  • Flatulence (1%-5%)

  • Dizziness (1%-5%)

  • Headache (1%-5%)

  • Upper respiratory infection (1%-5%)

  • Taste disturbance (1%-5%)

Learn more about metformin.


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