Fast Five Quiz: Intra-articular Injections for Knee Osteoarthritis

James Monroe Laborde, MD, MS


May 18, 2022

IAHA injections for knee OA are thought to restore synovial fluid lubrication and cushioning properties necessary for joint health. Unlike many of the standard-of-care oral pain medications often used for management of OA knee pain, IAHA injections have shown to be generally safe for patients with multiple comorbidities.

Numerous studies have demonstrated that IAHA injections provide significant pain relief in patients with early-moderate knee OA for up to 6 months. IAHA has been suggested for use in patients with refractory knee pain after treatment with acetaminophen, nonsteroidal anti-inflammatory drugs (NSAIDs), and symptomatic slow-acting drugs. In addition, studies have suggested that repeated IAHA injection may delay total knee arthroplasty.

Further, 65% of patients with knee OA are prescribed oral NSAIDs, which are not recommended for patients > 75 years of age. According to the European League Against Rheumatism, IAHA injections may be considered for pain relief and improved knee function in the elderly population.

Learn more about the management of knee OA.


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