PRP injections contain an autologous mixture of platelets and growth factors, which is thought to promote healing and repair in tissues with low healing potential. Currently, most guidelines recommend against the use of PRP as a potential knee OA therapy owing to the lack of high-quality randomized controlled trials and contradictory results. While many studies support the use of PRP for mild to moderate radiographic knee OA, others do not support its use.
According to the European League Against Rheumatism, PRP injections should be avoid during an exacerbation of knee OA.
Learn more about the management of knee OA.
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Cite this: James Monroe Laborde. Fast Five Quiz: Intra-articular Injections for Knee Osteoarthritis - Medscape - May 18, 2022.