Acute and chronic alcohol consumption may also be associated with thrombocytopenia. In persons with chronic liver disease, hypersplenism with secondary thrombocytopenia is not uncommon.
ITP is a primary illness occurring in an otherwise healthy person. Signs of chronic disease, infection, wasting, or poor nutrition indicate that the patient has another illness. Splenomegaly excludes the diagnosis of ITP.
In adults, thrombocytopenia may be a manifestation of systemic lupus erythematosus or acute or chronic leukemia. Thrombocytopenia may be a manifestation of a myelodysplastic syndrome, particularly in patients older than 60 years. In young children, ITP may manifest as a primary immune deficiency syndrome.
Thrombocytopenia is a recognized complication after infection with Epstein-Barr virus, varicella virus, cytomegalovirus, rubella virus, or hepatitis virus (A, B, or C). However, the most typical association is with a vaguely defined viral upper respiratory infection or gastroenteritis.
Learn more about the presentation of ITP.
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Cite this: Emmanuel C. Besa. Fast Five Quiz: Thrombocytopenia - Medscape - May 20, 2022.