Fast Five Quiz: Menopause

Richard Scott Lucidi, MD, FACOG

Disclosures

June 24, 2022

FSH is released by the pituitary gland to stimulate the development of follicles or eggs by the ovaries. The early stage of menopause is associated with a rise in serum FSH levels, even when levels of estrogen remain within the normal range. Women may experience increasing variability in menstrual cycle length, frequency of ovulation, and hormone fluctuations. As women grow older, the ovaries produce less estrogen and inhibin, disrupting the hypothalamic-pituitary-ovarian axis. With the lack of inhibition, there is increased FSH, luteinizing hormone, and follicular aromatase activity.

Levels of serum testosterone do not change during the menopausal transition.

Progesterone levels are dependent on ovulation. The transition to menopause is gradual, over a period of years, and women may still ovulate in the early stages of menopause. Low progesterone during the luteal phase may be suggestive of menopause; however, this is not a consistent finding and varies among women.

Menopause is not related to changes in thyroid function.

Learn more about menopause.

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