Rapid Rx Quiz: Sleep Aids

Mary L. Windle, PharmD


June 03, 2022

Zaleplon is not recommended in patients with severe hepatic impairment and a lower dose is recommended with mild to moderate hepatic impairment. It is contraindicated in anyone who has experienced hypersensitivity or complex sleep behaviors using the drug. In some patients with depression, symptoms can worsen; however, this is not related to treatment with selective serotonin reuptake inhibitors. Patients and clinicians should watch for signs for worsening symptoms, including suicidal ideation. No special risks from zaleplon use have been reported for patients with either moderate renal impairment; more research is needed to analyze the effects of zaleplon use in patients with severe renal impairment.

Learn more about zaleplon.

This Rapid Rx Quiz was excerpted and adapted from the Medscape articles OTC Melatonin Use Rises Fivefold Over 20 Years: Study, Melatonin (Herb/Supplement), Eszopiclone, Zaleplon, and Parkinson Disease.

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