Patients with childhood HPP may have mobility limitations, hypotonia, and gait abnormalities that significantly decrease their quality of life. In patients that are unable to participate in age-appropriate activities, physical therapy is indicated to improve functional status. If rehabilitation alone does not improve function, enzyme replacement therapy may be considered.
According to Marquez and colleagues, patients with juvenile HPP should avoid contact sports.
Learn more about HPP.
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Cite this: Eric T. Rush. Fast Five Quiz: Juvenile Hypophosphatasia Management - Medscape - Jul 22, 2022.