Other laboratory assessments in patients with HPP treated with asfotase alfa include:
Plasma inorganic pyrophosphate
Routine blood tests: complete blood cell count, liver function, and electrolytes
PTH can detect alterations in bone metabolism. PTH is dependent on long-term calcium levels and should be performed when calcium levels are persistently abnormal.
Anti-asfotase alfa IgG (antidrug antibody) tests may be considered in patients with poor response following successful treatment with enzyme replacement therapy.
Learn more about HPP.
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Cite this: Eric T. Rush. Fast Five Quiz: Juvenile Hypophosphatasia Management - Medscape - Jul 22, 2022.