Multiplex quantitative reverse transcriptase (RT)-polymerase chain reaction (PCR) assays for SARS-CoV-2 have been developed to determine variants of concern. They can also identify other mutations in the viral genome using single-nucleotide discriminating molecular beacons, according to the authors. Details of the two-tube multiplex RT-PCR assay revealed that it can detect eight distinct mutations on the coronavirus spike protein that have been identified in current variants of concern. The test is likely to be effective for detecting future variants that combine these mutations.
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This Rapid Review Quiz was excerpted and adapted from the Medscape articles: FDA Clears Diagnostic Test for Early Alzheimer's; Lyme Disease and Tick-Borne Illnesses; Blood Test Accurately Detects Cancer in People with Non-Specific Symptoms; Metastatic Breast Cancer; FDA Clears Diagnostic Test for Early Alzheimer's; Alzheimer Disease; A Faster, Cheaper Diagnostic Test for MS?; Multiple Sclerosis; Scientists Develop Test to Quickly Identify COVID-19 Variants; and Symptoms and Management of COVID-19.
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Cite this: Rapid Review Quiz: New Diagnostic Tests - Medscape - Jun 13, 2022.