Fast Five Quiz: COVID-19 Variants

Glenn Wortmann, MD

Disclosures

August 03, 2022

Omicron subvariants BA.4 and BA.5 S-proteins are identical with those of BA.2, with the exception of the addition of 69-70 deletion, F486V, and L452R. According to data reviewed by Mohapatra and colleagues, researchers have developed persistent Laplacian-based deep learning models by evaluating variant infectivity. Data from these researchers found that Omicron BA.3, BA.4, BA.5, BA.2.11, and BA.2.12.1 are more contagious than BA.2. However, BA.4 and BA.5 are about 36% more infectious than BA.2. Emerging reports of increasing infections with BA.4 and BA.5 variants suggest that these two lineages may possibly replace the BA.1, BA.2, and BA.3 lineages.

Learn more about BA.4 and BA.5.

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