Rapid Rx Quiz: Thyroid Drugs

Mary L. Windle, PharmD


July 20, 2022

A retrospective cohort study involving 705,307 adults who received hormone thyroid treatment found that patients with exogenous hyperthyroidism (eg, thyrotropin levels < 0.1 mIU/L: adjusted hazard ratio [AHR], 1.39; 95% CI, 1.32-1.47; FT4 levels > 1.9 ng/dL: AHR, 1.29; 95% CI, 1.20-1.40) and patients with exogenous hypothyroidism (eg, thyrotropin levels > 20 mIU/L: AHR, 2.67; 95% CI, 2.55-2.80; FT4 levels < 0.7 ng/dL: AHR, 1.56; 95% CI, 1.50-1.63) had increased risk for cardiovascular mortality compared with patients in the euthyroid range. Researchers suggest that this represents an easily modifiable parameter for mitigating cardiovascular mortality risk among patients receiving thyroid hormone treatment.

Learn more about thyroid disease.

This Rapid Rx Quiz was excerpted and adapted from the Medscape articles Hypothyroidism Medication, Liothyronine, Switching Among Generic Levothyroxine Products? No Problem, Hypothyroidism Medication, Levothyroxine, and Keeping Thyroid Treatment on Target Is Key for the Heart.

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