Rheumatic fever is characterized by the migratory nature of the arthritis, an elevated antistreptolysin O titer, and a more dramatic and prompt response to aspirin. Carditis and erythema marginatus may occur in adults, but chorea and subcutaneous nodules virtually never do. Elevations in erythrocyte sedimentation rate and C-reactive protein level are noted in both conditions, related to disease activity. Antinuclear antibodies are present in many patients with RA; however, test results for antibodies to most nuclear antigen subsets are often negative.
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Cite this: Herbert S. Diamond. Fast Five Quiz: Mimics of Rheumatoid Arthritis - Medscape - Jul 28, 2022.