Fast Five Quiz: Gastric Cancer Diagnosis

Daniel Catenacci, MD


August 24, 2022

Histologic examination of gastric tumors is required to establish a diagnosis of gastric cancer. A tissue sample can be obtained through a biopsy during upper endoscopy and is considered the gold standard for the diagnosis of gastric cancer. Upper endoscopy is highly sensitive and specific, with a diagnostic accuracy of 95%, according to Cabebe and colleagues. In addition, endoscopy allows for the direct visualization of the tumor, which typically appears as a friable, ulcerated mass.

Endoscopic ultrasound and CT are typically used for the staging of gastric cancer.

A liquid biopsy is a noninvasive approach that aims to detect circulating tumor DNA in the blood. It may be considered in patients with advanced or metastatic disease, particularly those who are unable to have a clinical biopsy, per the National Comprehensive Cancer Network (NCCN).

Learn more about gastric cancer.


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