Histologic examination of gastric tumors is required to establish a diagnosis of gastric cancer. A tissue sample can be obtained through a biopsy during upper endoscopy and is considered the gold standard for the diagnosis of gastric cancer. Upper endoscopy is highly sensitive and specific, with a diagnostic accuracy of 95%, according to Cabebe and colleagues. In addition, endoscopy allows for the direct visualization of the tumor, which typically appears as a friable, ulcerated mass.
Endoscopic ultrasound and CT are typically used for the staging of gastric cancer.
A liquid biopsy is a noninvasive approach that aims to detect circulating tumor DNA in the blood. It may be considered in patients with advanced or metastatic disease, particularly those who are unable to have a clinical biopsy, per the National Comprehensive Cancer Network (NCCN).
Learn more about gastric cancer.
Medscape © 2022 WebMD, LLC
Any views expressed above are the author's own and do not necessarily reflect the views of WebMD or Medscape.
Cite this: Daniel Catenacci. Fast Five Quiz: Gastric Cancer Diagnosis - Medscape - Aug 24, 2022.