Fast Five Quiz: Next-Generation Sequencing in Non–Small Cell Lung Cancer

Maurie Markman, MD


August 22, 2022

Nearly 30% of NSCLC harbor a mutation in the KRAS oncogene, making KRAS the most common oncogenic driver in lung cancer. The prevalence of mutations in the EGFR oncogenes overall is 19%, although it is much higher among Asian patients with lung adenocarcinoma. BRAF mutations occur in about 5% of patients. NTRK is rare, occurring in < 1% of patients.

Learn more about oncogenic driver mutations in NSCLC.


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