Fast Five Quiz: Homicidal Ideation

Stephen Soreff, MD

Disclosures

August 12, 2022

Alcohol and various illicit drugs are known to increase violent behavior. However, various prescription medications have also been linked to homicidal ideation. Varenicline, which is used to help with smoking cessation, has been connected to increases in violence. Other drugs associated with increased homicidal ideation include various antidepressants (notably fluoxetine and paroxetine), sedative/hypnotics, and medications used to treat attention-deficit/hyperactivity disorder. Evidence of an association is less well established for most antipsychotic drugs and anticonvulsant/mood stabilizers, other than levetiracetam. 

Learn more about varenicline.

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