Rapid Review Quiz: Vitamin D

Romesh Khardori, MD


September 06, 2022

A recent systematic review and meta-analysis of randomized controlled trials examined the effects of vitamin D supplementation on the muscular strength and mobility in postmenopausal women with vitamin D deficiency, which was defined as a circulating level of 25(OH)D < 20 ng/ml (50 nmol/L). The study analyzed the effect size of HGS and TUG; 19 trials were included in the systematic review, and 13 of which were eligible for the meta-analysis.

Vitamin D supplementation produced a significant increase in HGS, a measurement of muscle strength, and an insignificant decrease in TUG. Subgroup analysis revealed that vitamin D supplementation increased HGS in patients older than 60 years, both in those with a normal baseline vitamin D level > 75 nmol/L (> 30 ng/mL) and in those without calcium supplementation.

Learn more about menopause.

This Rapid Review Quiz was excerpted and adapted from the Medscape articles Vitamin D Doesn't Reduce Type 2 Diabetes Risk…Or Does It? , Vitamin D , Low Vitamin D Tied to Breast Cancer Risk in Hispanic Women , Vitamin D Deficiency and Related Disorders , Study: Vitamin D Deficiency Linked to Severe COVID , COVID-19 Pulmonary Management , Irritable Bowel Syndrome , and Menopause .

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