For patients with blast phase CML, induction chemotherapy in addition to a TKI is recommended, with the type of induction chemotherapy being guided by the myeloid or lymphoid lineage of the blasts. If a patient is not a candidate for induction chemotherapy, NCCN guidelines recommend a TKI; steroids may be added for patients with lymphoid blasts. A clinical trial may also be considered.
Learn more about guidelines for the management of CML.
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Cite this: Emmanuel C. Besa. Fast Five Quiz: Chronic Myelogenous Leukemia Management - Medscape - Sep 21, 2022.