Fast Five Quiz: COVID-19 Omicron Variant

Michael Stuart Bronze, MD


September 20, 2022

Editor's Note: The information in this quiz is current as of September 20, 2022. For the most recent COVID information, see

Many people now have a certain level of immunity against COVID-19, owing to either vaccination or previous SARS-CoV-2 infection. This acquired immunity has pressured the virus to rapidly spawn variants that are able to evade SARS-CoV-2 neutralizing antibodies. The virus's evolution enables COVID-19 to continue to affect the global community, challenging researchers to quickly understand and respond to the latest variants and their distinct characteristics.

Omicron (B.1.1.529) is a heavily mutated variant of SARS-CoV-2 with several diverse lineages and sublineages, including BA.1, BA.1.1, BA.2, BA.2.12.1, BA.3, BA.4, and BA.5. The World Health Organization designated Omicron a variant of concern on November 26, 2021, just days after the first genome had been uploaded upon its discovery in South Africa and Botswana. Since that time, several sublineages of Omicron have become dominant across the globe.

How much do you know about the COVID-19 Omicron variant? Test your knowledge with this quick quiz.


Comments on Medscape are moderated and should be professional in tone and on topic. You must declare any conflicts of interest related to your comments and responses. Please see our Commenting Guide for further information. We reserve the right to remove posts at our sole discretion.