In patients with anal fissures that are irregular and/or off the midline, or in whom an underlying illness is present (eg, squamous cell cancer, Crohn's disease, AIDS), appropriate lab tests should be obtained. These can include:
Erythrocyte sedimentation rate
Biopsy of fissure or lesions (as warranted)
Stool and viral cultures
HIV testing
When ordinary anal fissures are located on the anterior or posterior midline, no laboratory tests are necessary.
Learn more about the workup of anal fissure.
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Cite this: Richard H. Sinert. Fast Five Quiz: Anal Fissures and Fistulas - Medscape - Sep 15, 2022.
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