These advances came in this order: Smallpox vaccine was first used in 1799; the cause and prevention of puerperal fever, also called childbed fever, was identified by Oliver Wendell Holmes in 1843; heat-killed vaccines were first developed in the 1890s and early 1900s; and Thomas Weller, John Enders, and Frederick Robbins grew poliovirus in culture in 1949, paving the way for vaccines against polio, mumps, measles, rubella, and chickenpox.
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Cite this: Medscape Staff. Trivia Quiz: Major Medical Milestones - Medscape - Sep 26, 2022.