Fast Five Quiz: Dry Eye Disease (Keratoconjunctivitis Sicca) Etiology and Pathophysiology

Christina R. Prescott, MD, PhD

Disclosures

November 10, 2022

According to Chiang and colleagues, primary lacrimal gland deficiencies in non–SS-related aqueous-deficient dry eye that may impair aqueous production include:

  • Idiopathic

  • Age-related dry eye

  • Congenital alacrima (eg, Riley-Day syndrome)

  • Familial dysautonomia

The underlying cause of primary SS aqueous-deficient dry eye is unknown.

Secondary SS may be associated with:

  • Rheumatoid arthritis

  • Systemic lupus erythematosus

  • Progressive systemic sclerosis (scleroderma)

  • Psoriatic arthritis

  • Primary biliary cirrhosis

  • Interstitial nephritis

  • Polymyositis

  • Dermatomyositis

  • Granulomatosis with polyangiitis (formerly Wegener granulomatosis)

  • Polyarteritis nodosa

  • Hashimoto thyroiditis

  • Lymphocytic interstitial pneumonitis

  • Idiopathic thrombocytopenic purpura

  • Hypergammaglobulinemia

  • Waldenström macroglobulinemia

Learn more about the etiology of aqueous-deficient dry eye.

Comments

3090D553-9492-4563-8681-AD288FA52ACE
Comments on Medscape are moderated and should be professional in tone and on topic. You must declare any conflicts of interest related to your comments and responses. Please see our Commenting Guide for further information. We reserve the right to remove posts at our sole discretion.

processing....